ceesdekker.net - An Overview
ceesdekker.net - An Overview
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‘It had been just a make a difference of picking up a book on cell biology and beginning to go through. I had originate from a entire world of ultra-high vacuums, cryostats and quantum phenomena, and now I had been Doing work at space temperature with molecular biology kits.
Sculpting nano-electrodes which has a transmission electron beam for electrical and geometrical characterization of nanoparticles.
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Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes
What distinguishes biology from chemistry is usually that these elements alongside one another make up a residing procedure. The key of reported daily life, I think, lies while in the interactions, the interaction of Individuals molecules. The massive issue about the origin of lifetime is still unanswered. How did we ever evolve from very simple molecules to the exceptionally sophisticated units we see nowadays? We do not know. I want to work on These types of large, open issues.’
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Knowledge essential procedures regulating the spatial and dynamic organisation with the DNA in Stay cells.
‘The fantastically refined way through which factors in nature functionality hardly ever ceases to amaze me. If we clear up the puzzle of how daily life came into being, I hope that my amazement for the complexity of development can have elevated and with it my awe with the greatness on the Creator.’
Considering the fact that 2000 he moved to solitary-molecule biophysics and nanobiology, with research from scientific tests of DNA loop extrusion and supercoiling to DNA translocation by means of nanopores. More not long ago his study has centered on learning chromatin composition and cell division with micro organism on chip, even though he is also trying to finally Construct artificial cells from the bottom up.
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2008, initially observation of protein-coated DNA translocation by nanopores; fixed the origin with the electrophoretic pressure on DNA in nanopores; uncovered a major velocity boost of microtubules in electric fields; found an anomalous electro-hydrodynamic orientation of microtubules; and resolved the origin of sounds in carbon nanotubes in liquid
2013, managed shaping of live bacterial cells into arbitrary designs; and discovery of spontaneous fluctuations within the handedness of histone tetrasomes